Epigenetics: A Revolutionary Science


Different environmental factors contribute to epigenetic changes leading to alteration of molecules bound to Deoxyribonucleic acid (DNA) and protein structure. The changes in Deoxyribonucleic acid formation results in slight changes in gene activity. The epigenetic condition tends to produce changes in switching gene functions and vice-versa. There are different environmental factors with a direct impact on gene functions and effects on overall human genetic developments; including diet and drugs.


First, diet is considered an important regulator of human gene expression (MyPsychLab. (n.d.). Dietary patterns are expressed through the formation of several dietary compounds regulating the function of the gene through polyunsaturated fatty acids (PUFA). Thus, the patterns directly affect the ability of genes to effectively contribute to lipid and glycolytic synthesis processes. Therefore, the impacts of diet on gene expression are determined by the ability to distribute macronutrients leading to gene regulation. The outcome is a limited protein that affects gene expression to change cell metabolism.


In addition, the dietary pattern contributes to significant human genetic developments. Generally, genetic variation affects dietary requirements. The effects are attributed to the notion of macronutrients and metabolite function leading to changes in gene expressions (Cull et al., 2017). The concepts are attributed to key protein functions which are critical in enhancing the control of cell division or differentiation leading to significant changes in genetic development. The components of dietary fibre contribute to fibre elements influencing gene expression (MyPsychLab. (n.d.). Such changes lead to hormonal signalling contributing to the ability of the gene to respond to environmental stimuli. Besides, some dietary patterns limit the levels of nutrient absorption influencing the overall function and structure of genes. Therefore, it is necessary to identify essential dietary patterns to create a positive genetic response.


The transition from infrequent use of drugs leads to massive genetic changes affecting the overall human genetic development. These are influenced by the capability of drugs to change overall gene expression restructuring neural circuits and rational functions of the brain. Therefore, the number of human genes in the body tends to develop strategic changes to respond to drugs induced in the human systems (Yang et al., 2018). The overall changes are attributed to compulsive behaviour enhanced by drug addiction affecting genetic response to physiological changes such as stress, metabolic energy and temperature variation. Typically, the developments and alteration levels in gene expression are common among individuals suffering from addiction to different agents.


Addiction is associated with the changes in the structure and the overall function of the brain which involve the role of neuronal networks and cell composition. The functions of the cell contribute to rapid changes in gene expression illustrating the changes in genetic formation and functions in the human body. The transcriptional changes in genetic functions are influenced by dynamic alteration of signal pathways (Donkin & Barrès, 2018). Thus, the effects of drugs on genetic expression are attributed to widespread changes in molecular and cellular dysregulation affecting the overall development and functions of gene pathways. Thus, the identified molecular and cellular changes are attributed to adaptations designed for epigenetic regulation and gene expression that is measured in the cells.


Different environmental factors can lead to a direct impact on gene functions and affect overall human genetic developments such as dieting and drugs.

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